Identifying loci affecting trait variability and detecting interactions in genome-wide association studies

Identification of genetic variants with effects on trait variability can provide insights into the biological mechanisms that control variation and can identify potential interactions. We propose a two-degree-of-freedom test for jointly testing mean and variance effects to identify such variants. We...

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Bibliographic Details
Main Authors: Young, A, Wauthier, F, Donnelly, P
Format: Journal article
Language:English
Published: Springer Nature 2018