Acetylcholine and norepinephrine stimulate the release of corticotropin-releasing factor-41 from the rat hypothalamus in vitro.

The effects of the two putative neurotransmitters acetylcholine and norepinephrine on immunoreactive CRF-41 release from incubated rat hypothalami were studied. Acetylcholine at concentrations of 10(-11) to 10(-7) M stimulated CRF-41 release. This effect was blocked in a dose-dependent manner by the...

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Bibliographic Details
Main Authors: Tsagarakis, S, Holly, J, Rees, L, Besser, G, Grossman, A
Format: Journal article
Language:English
Published: 1988