Affinity measured by microcluster.

Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation "translate" BCR affinity for antigen into B cell responsiveness.

Bibliografiset tiedot
Päätekijät: Fooksman, DR, Dustin, M
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2010
Kuvaus
Yhteenveto:Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation "translate" BCR affinity for antigen into B cell responsiveness.