Affinity measured by microcluster.

Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation "translate" BCR affinity for antigen into B cell responsiveness.

Бібліографічні деталі
Автори: Fooksman, DR, Dustin, M
Формат: Journal article
Мова:English
Опубліковано: 2010
Опис
Резюме:Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation "translate" BCR affinity for antigen into B cell responsiveness.