Affinity measured by microcluster.
Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation "translate" BCR affinity for antigen into B cell responsiveness.
Những tác giả chính: | , |
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Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
2010
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Tóm tắt: | Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation "translate" BCR affinity for antigen into B cell responsiveness. |
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