Affinity measured by microcluster.

Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation "translate" BCR affinity for antigen into B cell responsiveness.

Chi tiết về thư mục
Những tác giả chính: Fooksman, DR, Dustin, M
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2010
Miêu tả
Tóm tắt:Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation "translate" BCR affinity for antigen into B cell responsiveness.