HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL response.

Mutational escape from the CTL response represents a major driving force for viral diversification in HIV-1-infected adults, but escape during infancy has not been described previously. We studied the immune response of perinatally infected children to an epitope (B57-TW10) that is targeted early du...

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Bibliographic Details
Main Authors: Feeney, M, Tang, Y, Pfafferott, K, Roosevelt, K, Draenert, R, Trocha, A, Yu, X, Verrill, C, Allen, T, Moore, C, Mallal, S, Burchett, S, McIntosh, K, Pelton, S, John, S, Hazra, R, Klenerman, P, Altfeld, M, Walker, B, Goulder, P
Format: Journal article
Language:English
Published: 2005