Glycosyl phenylthiosulfonates (glyco-PTS): novel reagents for glycoprotein synthesis.

Controlled site-selective glycosylation can be achieved by combining site-directed cysteine mutagenesis with chemical modification of the introduced thiol; a new class of more efficient chemoselective reagents, glycosyl phenylthiosulfonates, allow rapid glycosylations of representative simple thiols...

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Detalhes bibliográficos
Main Authors: Gamblin, D, Garnier, P, Ward, S, Oldham, N, Fairbanks, A, Davis, B
Formato: Journal article
Idioma:English
Publicado em: 2003