Structure-activity studies of a macrocyclic peptide inhibitor of histone lysine demethylase 4A

The combination of genetic code reprogramming and mRNA display is a powerful approach for the identification of macrocyclic peptides with high affinities to a target of interest. We have previously used such an approach to identify a potent inhibitor (CP2) of the human KDM4A and KDM4C lysine demethy...

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Huvudupphovsmän: Passioura, T, Bhushan, B, Tumber, A, Kawamura, A, Suga, H
Materialtyp: Journal article
Publicerad: Elsevier 2018