Synthetic negative feedback circuits using engineered small RNAs

Negative feedback is known to enable biological and man-made systems to perform reliably in the face of uncertainties and disturbances. To date, synthetic biological feedback circuits have primarily relied upon protein-based, transcriptional regulation to control circuit output. Small RNAs (sRNAs) a...

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Hlavní autoři: Kelly, C, Harris, A, Steel, H, Hancock, E, Heap, J, Papachristodoulou, A
Médium: Journal article
Jazyk:English
Vydáno: Oxford University Press 2018