Synthetic negative feedback circuits using engineered small RNAs

Negative feedback is known to enable biological and man-made systems to perform reliably in the face of uncertainties and disturbances. To date, synthetic biological feedback circuits have primarily relied upon protein-based, transcriptional regulation to control circuit output. Small RNAs (sRNAs) a...

Full description

Bibliographic Details
Main Authors: Kelly, C, Harris, A, Steel, H, Hancock, E, Heap, J, Papachristodoulou, A
Format: Journal article
Language:English
Published: Oxford University Press 2018