Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing.
This article outlines the need for a homeostatic response to alterations in cellular oxygenation. It describes work on erythropoietin control that led to the discovery of the hypoxia-inducible transcription factor (HIF-1) and the parallel recognition that this system was responsive to a widespread o...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2009
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