Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing.

This article outlines the need for a homeostatic response to alterations in cellular oxygenation. It describes work on erythropoietin control that led to the discovery of the hypoxia-inducible transcription factor (HIF-1) and the parallel recognition that this system was responsive to a widespread o...

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Autors principals: Webb, J, Coleman, M, Pugh, C
Format: Journal article
Idioma:English
Publicat: 2009