Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance.

BACKGROUND: Research for the use of biomarkers in osteoarthritis (OA) is promising, however, adequate discrimination between patients and controls may be hampered due to innate differences. We set out to identify loci influencing levels of serum cartilage oligomeric protein (sCOMP) and urinary C-tel...

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Main Authors: Ramos, Y, Metrustry, S, Arden, N, Bay-Jensen, A, Beekman, M, de Craen, A, Cupples, L, Esko, T, Evangelou, E, Felson, D, Hart, D, Ioannidis, J, Karsdal, M, Kloppenburg, M, Lafeber, F, Metspalu, A, Panoutsopoulou, K, Slagboom, P, Spector, T, van Spil, E, Uitterlinden, A, Zhu, Y, Valdes, A, van Meurs, J, Meulenbelt, I
Format: Journal article
Language:English
Published: BMJ Publishing Group 2014