BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells

Bromodomain-containing protein 4 (BRD4) is a member of the bromo- and extraterminal (BET) domain-containing family of epigenetic readers which is under intensive investigation as a target for anti-tumor therapy. BRD4 plays a central role in promoting the expression of select subsets of genes includi...

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Main Authors: Nagarajan, S, Bedi, U, Budida, A, Hamdan, FH, Mishra, VK, Najafova, Z, Xie, W, Alawi, M, Indenbirken, D, Knapp, S, Chiang, C-M, Grundhoff, A, Kari, V, Scheel, CH, Wegwitz, F, Johnsen, SA
Format: Journal article
Language:English
Published: Oxford University Press 2016