Induced disruption of the iron-regulatory hormone hepcidin inhibits acute inflammatory hypoferremia
Withdrawal of iron from serum (hypoferremia) is a conserved innate immune antimicrobial strategy that can withhold this critical nutrient from invading pathogens, impairing their growth. Hepcidin (Hamp1) is the master regulator of iron and its expression is induced by inflammation. Mice...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
Karger
2016
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