Prolonged wakefulness alters neuronal responsiveness to local electrical stimulation of the neocortex in awake rats.

Prolonged wakefulness or a lack of sleep lead to cognitive deficits, but little is known about the underlying cellular mechanisms. We recently found that sleep deprivation affects spontaneous neuronal activity in the neocortex of sleeping and awake rats. While it is well known that synaptic response...

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Bibliographic Details
Main Authors: Vyazovskiy, V, Olcese, U, Cirelli, C, Tononi, G
Format: Journal article
Language:English
Published: 2012