Experimental generation and computational modeling of intracellular pH gradients in cardiac myocytes.
It is often assumed that pH(i) is spatially uniform within cells. A double-barreled microperfusion system was used to apply solutions of weak acid (acetic acid, CO(2)) or base (ammonia) to localized regions of an isolated ventricular myocyte (guinea pig). A stable, longitudinal pH(i) gradient (up to...
| Main Authors: | , , , |
|---|---|
| 格式: | Journal article |
| 语言: | English |
| 出版: |
2005
|