The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells.
The ch-TOG/XMAP215 family of proteins bind directly to microtubules and appear to play an essential role in stabilizing spindle microtubules. These proteins stabilize microtubules mainly by influencing microtubule plus-end dynamics, yet, in vivo, they are all strongly concentrated at spindle poles,...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2003
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