Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus

Identifying genetic determinants of reproductive success may highlight mechanisms underlying fertility and also identify alleles under present-day selection. Using data in 785,604 individuals of European ancestry, we identify 43 genomic loci associated with either number of children ever born (NEB)...

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Main Authors: Mathieson, I, Day, FR, Barban, N, Tropf, FC, Brazel, D, Vaez, A, van Zuydam, N, Bitarello, BD, Snieder, H, den Hoed, M, Ong, K, Mills, MC, Perry, JRB
格式: Working paper
出版: bioRxiv 2020