Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus

Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus

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Identifying genetic determinants of reproductive success may highlight mechanisms underlying fertility and also identify alleles under present-day selection. Using data in 785,604 individuals of European ancestry, we identify 43 genomic loci associated with either number of children ever born (NEB)...

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Bibliographic Details
Main Authors: Mathieson, I, Day, FR, Barban, N, Tropf, FC, Brazel, D, Vaez, A, van Zuydam, N, Bitarello, BD, Snieder, H, den Hoed, M, Ong, K, Mills, MC, Perry, JRB
Format: Working paper
Published: bioRxiv 2020

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