Detection of alpha-synuclein conformational variants from gastro-intestinal biopsy tissue as a potential biomarker for Parkinson's disease

<h4>Aims</h4> <p>Gastrointestinal (GI) a-synuclein (aSyn) detection as a potential biomarker of Parkinson’s disease (PD) is challenged by conflicting results of recent studies. To increase sensitivity and specificity, we applied three techniques to detect different conformations o...

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Bibliographic Details
Main Authors: Ruffmann, C, Bengoa-Vergniory, N, Poggiolini, I, Ritchie, D, Hu, M, Alegre-Abarrategui, J, Parkkinen, L
Format: Journal article
Language:English
Published: Wiley 2018