Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease.

Celiac disease is a genetic condition that results in a debilitating immune reaction in the gut to antigens in grain. The antigenic peptides recognized by the T cells that cause this disease are incompletely defined. Our understanding of the epitopes of pathogenic CD4(+ )T cells is based primarily o...

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Bibliographic Details
Main Authors: Tye-Din, J, Stewart, J, Dromey, J, Beissbarth, T, van Heel, D, Tatham, A, Henderson, K, Mannering, S, Gianfrani, C, Jewell, D, Hill, A, McCluskey, J, Rossjohn, J, Anderson, R
Format: Journal article
Language:English
Published: 2010