Structures of the Shigella flexneri type 3 secretion system protein MxiC reveal conformational variability amongst homologues.

Many Gram-negative pathogenic bacteria use a complex macromolecular machine, known as the type 3 secretion system (T3SS), to transfer virulence proteins into host cells. The T3SS is composed of a cytoplasmic bulb, a basal body spanning the inner and outer bacterial membranes, and an extracellular ne...

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Bibliographic Details
Main Authors: Deane, J, Roversi, P, King, C, Johnson, S, Lea, S
Format: Journal article
Language:English
Published: 2008