Outcome of azacitidine therapy in acute myeloid leukemia is not improved by concurrent vorinostat therapy but is predicted by a diagnostic molecular signature

<strong>Purpose:</strong> Azacitidine (AZA) is a novel therapeutic option in older patients with acute myeloid leukemia (AML), but its rational utilization is compromised by the fact that neither the determinants of clinical response nor its mechanism of action are defined. Co-administra...

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Bibliographic Details
Main Authors: Craddock, C, Houlton, A, Quek, L, Ferguson, P, Gbandi, E, Roberts, C, Metzner, M, Garcia-Martin, N, Kennedy, A, Hamblin, A, Raghavan, M, Nagra, S, Dudley, L, Wheatley, K, McMullin, M, Pillai, S, Kelly, R, Siddique, S, Dennis, M, Cavenagh, J, Vyas, P
Format: Journal article
Language:English
Published: American Association for Cancer Research 2017