Fine tuning gene expression levels in mammalian cells with engineered microRNA target sites
<p>Precise, analogue regulation of gene expression is critical for development, homeostasis and regeneration in mammals. In contrast, widely employed experimental and therapeutic approaches such as knock-in/out strategies are more suitable for binary control of gene activity, while RNA interfe...
Main Author: | |
---|---|
Other Authors: | |
Format: | Thesis |
Published: |
2018
|
Subjects: |