METTL4 is an snRNA m6Am methyltransferase that regulates RNA splicing
Prif Awduron: | Chen, H, Gu, L, Orellana, EA, Wang, Y, Guo, J, Liu, Q, Wang, L, Shen, Z, Wu, H, Gregory, RI, Xing, Y, Shi, Y |
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Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
Springer Nature
2020
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Eitemau Tebyg
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METTL4 catalyzes m6Am methylation in U2 snRNA to regulate pre-mRNA splicing
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Loss of the RNA trimethylguanosine cap is compatible with nuclear accumulation of spliceosomal snRNAs but not pre-mRNA splicing or snRNA processing during animal development.
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