Stress‐induced Rab11a‐exosomes induce amphiregulin‐mediated cetuximab resistance in colorectal cancer

Exosomes are secreted vesicles made intracellularly in the endosomal system. We have previously shown that exosomes are not only made in late endosomes, but also in recycling endosomes marked by the monomeric G‐protein Rab11a. These vesicles, termed Rab11a‐exosomes, are preferentially secreted under...

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Bibliographic Details
Main Authors: Mason, JD, Marks, E, Fan, S, McCormick, K, Wilson, C, Harris, AL, Hamdy, FC, Cunningham, C, Goberdhan, DCI
Format: Journal article
Language:English
Published: Wiley Open Access 2024