Structure and dynamics of the E. coli chemotaxis core signaling complex by cryo-electron tomography and molecular simulations

To enable the processing of chemical gradients, chemotactic bacteria possess large arrays of transmembrane chemoreceptors, the histidine kinase CheA, and the adaptor protein CheW, organized as coupled core-signaling units (CSU). Despite decades of study, important questions surrounding the molecular...

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Bibliographic Details
Main Authors: Cassidy, C, Himes, B, Sun, D, Ma, J, Zhao, G, Parkinson, J, Stansfeld, P, Luthey-Schulten, Z, Zhang, P
Format: Journal article
Language:English
Published: Nature Research 2020