The role of hypoxia-inducible factors in organ donation and transplantation: the current perspective and future opportunities.

Hypoxia-inducible factors are the universal cellular oxygen-sensitive transcription factors that activate a number of hypoxia responsive genes, some of which are responsible for protective cellular functions. During organ donation, allografts are exposed to significant periods of hypoxia and ischemi...

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Bibliographic Details
Main Authors: Akhtar, M, Sutherland, A, Huang, H, Ploeg, R, Pugh, C
Format: Journal article
Language:English
Published: 2014