Out of balance: R-loops in human disease
R-loops are cellular structures composed of an RNA/DNA hybrid, which is formed when the RNA hybridises to a complementary DNA strand and a displaced single-stranded DNA. R-loops have been detected in various organisms from bacteria to mammals and play crucial roles in regulating gene expression, DNA...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Public Library of Science
2014
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