Out of balance: R-loops in human disease
R-loops are cellular structures composed of an RNA/DNA hybrid, which is formed when the RNA hybridises to a complementary DNA strand and a displaced single-stranded DNA. R-loops have been detected in various organisms from bacteria to mammals and play crucial roles in regulating gene expression, DNA...
Những tác giả chính: | Groh, M, Gromak, N |
---|---|
Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
Public Library of Science
2014
|
Những quyển sách tương tự
-
Out of balance: R-loops in human disease.
Bằng: Matthias Groh, et al.
Được phát hành: (2014-09-01) -
R-loop immunoprecipitation: a method to detect R-loop interacting factors
Bằng: Beghè, C, et al.
Được phát hành: (2022) -
R-loops associated with triplet repeat expansions promote gene silencing in Friedreich ataxia and fragile X syndrome
Bằng: Groh, M, et al.
Được phát hành: (2014) -
RNA/DNA hybrid interactome identifies DXH9 as a molecular player in transcriptional termination and R-loop-associated DNA damage
Bằng: Cristini, A, et al.
Được phát hành: (2018) -
SOSS-INTAC: a new gatekeeper of genomic integrity at the interface of transcription and R-loops
Bằng: Gromak, N
Được phát hành: (2023)