Out of balance: R-loops in human disease

Out of balance: R-loops in human disease

R-loops are cellular structures composed of an RNA/DNA hybrid, which is formed when the RNA hybridises to a complementary DNA strand and a displaced single-stranded DNA. R-loops have been detected in various organisms from bacteria to mammals and play crucial roles in regulating gene expression, DNA...

書目詳細資料
Main Authors:	Groh, M, Gromak, N
格式:	Journal article
語言:	English
出版:	Public Library of Science 2014

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