Evolutionary genetics of human enterovirus 71: origin, population dynamics, natural selection, and seasonal periodicity of the VP1 gene.

Human enterovirus 71 (EV-71) is one of the major etiologic causes of hand, foot, and mouth disease (HFMD) among young children worldwide, with fatal instances of neurological complications becoming increasingly common. Global VP1 capsid sequences (n = 628) sampled over 4 decades were collected and s...

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Bibliographic Details
Main Authors: Tee, K, Lam, T, Chan, Y, Bible, J, Kamarulzaman, A, Tong, C, Takebe, Y, Pybus, O
Format: Journal article
Language:English
Published: 2010