Efficacy and safety of apremilast, an oral phosphodiesterase 4 inhibitor, in ankylosing spondylitis.

OBJECTIVES: To evaluate the efficacy and safety of an oral phosphodiesterase 4 inhibitor, apremilast, in treatment of ankylosing spondylitis (AS) by monitoring symptoms and signs in a pilot study including exploratory investigation of effects of PDE4 inhibition on blood biomarkers of bone biology....

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Bibliographic Details
Main Authors: Pathan, E, Abraham, S, Van Rossen, E, Withrington, R, Keat, A, Charles, P, Paterson, E, Chowdhury, M, McClinton, C, Taylor, P
Format: Journal article
Language:English
Published: 2013