3D growth of cancer cells elicits sensitivity to kinase inhibitors but not lipid metabolism modifiers

3D growth of cancer cells elicits sensitivity to kinase inhibitors but not lipid metabolism modifiers

Tumor cells exhibit altered lipid metabolism compared with normal cells. Cell signaling kinases are important for regulating lipid synthesis and energy storage. How upstream kinases regulate lipid content, versus direct targeting of lipid-metabolizing enzymes, is currently unexplored. We evaluated i...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Jones, DT, Valli, A, Haider, S, Zhang, Q, Smethurst, EA, Schug, ZT, Peck, B, Aboagye, EO, Critchlow, SE, Schulze, A, Gottlieb, E, Wakelam, MJO, Harris, AL
التنسيق: Journal article
اللغة:English
منشور في: American Association for Cancer Research 2018

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