Sequence of Crm1/exportin 1 mutant alleles reveals critical sites associated with multidrug resistance.

We have previously shown that genes involved in a novel pathway of multidrug resistance (MDR) in the fission yeast Schizosaccharomyces pombe are functionally conserved in human cells (V. Spataro et al. (1997) J Biol Chem 272: 30470-30475). The human homologue of one of these genes, hCRM1, has recent...

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Detalhes bibliográficos
Principais autores: Carobbio, S, Realini, C, Norbury, C, Toda, T, Cavalli, F, Spataro, V
Formato: Journal article
Idioma:English
Publicado em: 2001