Sequence of Crm1/exportin 1 mutant alleles reveals critical sites associated with multidrug resistance.

Sequence of Crm1/exportin 1 mutant alleles reveals critical sites associated with multidrug resistance.

We have previously shown that genes involved in a novel pathway of multidrug resistance (MDR) in the fission yeast Schizosaccharomyces pombe are functionally conserved in human cells (V. Spataro et al. (1997) J Biol Chem 272: 30470-30475). The human homologue of one of these genes, hCRM1, has recent...

Bibliografske podrobnosti
Main Authors:	Carobbio, S, Realini, C, Norbury, C, Toda, T, Cavalli, F, Spataro, V
Format:	Journal article
Jezik:	English
Izdano:	2001

Podobne knjige/članki

Sequence of crm1 mutant alleles in fission yeast reveals critical sites associated with multidrug resistance that are conserved in human CRM1.
od: Spataro, V, et al.
Izdano: (2000)

Structural Basis of Targeting the Exportin CRM1 in Cancer
od: Achim Dickmanns, et al.
Izdano: (2015-09-01)

Structural determinants of nuclear export signal orientation in binding to exportin CRM1
od: Ho Yee Joyce Fung, et al.
Izdano: (2015-09-01)

Rescue of Mitochondrial Function in Hutchinson-Gilford Progeria Syndrome by the Pharmacological Modulation of Exportin CRM1
od: Feliciano Monterrubio-Ledezma, et al.
Izdano: (2023-01-01)

Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore
od: Xun X Bao, et al.
Izdano: (2018-05-01)

Rrp12 and the Exportin Crm1 participate in late assembly events in the nucleolus during 40S ribosomal subunit biogenesis.
od: Giulia Moriggi, et al.
Izdano: (2014-12-01)

Frequency of the MDR1 mutant allele associated with multidrug sensitivity in dogs from Brazil
od: Monobe MM, et al.
Izdano: (2015-04-01)

Nuclear entry and export of FIH are mediated by HIF1α and exportin1 respectively
od: Wang, Y, et al.
Izdano: (2018)

XPO1/Exportin-1 in Acute Myelogenous Leukemia; Biology and Therapeutic Targeting
od: Øystein Bruserud, et al.
Izdano: (2025-01-01)

Effect of Exportin 1/XPO1 Nuclear Export Pathway Inhibition on Coronavirus Replication
od: Masmudur M. Rahman, et al.
Izdano: (2025-02-01)

Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma
od: Eline Boons, et al.
Izdano: (2015-09-01)

Importins and Exportins Regulating Allergic Immune Responses
od: Ankita Aggarwal, et al.
Izdano: (2014-01-01)

The significance of gradient expression of chromosome region maintenance protein 1 (exportin1) in large cell lymphoma
od: Jithma P. Abeykoon, et al.
Izdano: (2021-03-01)

Exportin 1‐mediated nuclear/cytoplasmic trafficking controls drug sensitivity of classical Hodgkin's lymphoma
od: Mélody Caillot, et al.
Izdano: (2023-12-01)

P006 (0037) RECURRENT EXPORTIN 1 MUTATIONS IN PATIENTS WITH CLASSICAL HODGKIN LYMPHOMA
Izdano: (2018-10-01)

Nuclear exportin receptor CAS regulates the NPI-1-mediated nuclear import of HIV-1 Vpr.
od: Eri Takeda, et al.
Izdano: (2011-01-01)

The Role of Exportin-5 in MicroRNA Biogenesis and Cancer
od: Ke Wu, et al.
Izdano: (2018-04-01)

Exportin 4 DNA promoter methylation in liver fibrosis.
od: Ziyan Pan, et al.
Izdano: (2024-01-01)

Exportin 4 DNA promoter methylation in liver fibrosis
od: Ziyan Pan, et al.
Izdano: (2024-01-01)

In vitro toxicity and efficacy of verdinexor, an exportin 1 inhibitor, on opportunistic viruses affecting immunocompromised individuals.
od: Douglas G Widman, et al.
Izdano: (2018-01-01)

The nuclear export protein exportin‐1 in solid malignant tumours: From biology to clinical trials
od: Chuanxi Lai, et al.
Izdano: (2024-05-01)

Formation of a Trimeric Xpo1-Ran[GTP]-Ded1 Exportin Complex Modulates ATPase and Helicase Activities of Ded1.
od: Glenn Hauk, et al.
Izdano: (2015-01-01)

Expression and function of exportin 6 in full-grown and growing porcine oocytes
od: Asuka ONUMA, et al.
Izdano: (2019-06-01)

Exportin-T: A Novel Prognostic Predictor and Potential Therapeutic Target for Neuroblastoma
od: Li-Jia Pan, et al.
Izdano: (2021-09-01)

Exportin-1-Dependent Nuclear Export of DEAD-box Helicase DDX3X is Central to its Role in Antiviral Immunity
od: Steven M. Heaton, et al.
Izdano: (2019-09-01)

Small Molecule Inhibitors of CRM1
od: Bibiana I. Ferreira, et al.
Izdano: (2020-05-01)

CRM1 Inhibitors for Antiviral Therapy
od: Cynthia Mathew, et al.
Izdano: (2017-06-01)

Multiomics Analysis of Exportin Family Reveals XPO1 as a Novel Target for Clear Cell Renal Cell Carcinoma
od: Yanhong Hao, et al.
Izdano: (2025-01-01)

Effects of cadmium on osteoblast cell line: Exportin 1 accumulation, p-JNK activation, DNA damage and cell apoptosis
od: Ling Ou, et al.
Izdano: (2021-01-01)

Exportin-mediated nucleocytoplasmic transport maintains Pch2 homeostasis during meiosis.
od: Esther Herruzo, et al.
Izdano: (2023-11-01)

Exportin 4 depletion leads to nuclear accumulation of a subset of circular RNAs
od: Liang Chen, et al.
Izdano: (2022-10-01)

Detection and prognostic value of recurrent exportin 1 mutations in tumor and cell-free circulating DNA of patients with classical Hodgkin lymphoma
od: Vincent Camus, et al.
Izdano: (2016-09-01)

Investigation of Exportin 5 (XPO5) mRNA expression in breast cancer patients
od: Samira Shakerizadeh, et al.
Izdano: (2017-01-01)

Laminin-111 and the Level of Nuclear Actin Regulate Epithelial Quiescence via Exportin-6
od: Ana Paula Zen Petisco Fiore, et al.
Izdano: (2017-06-01)

eEF1A Mediates the Nuclear Export of SNAG-Containing Proteins via the Exportin5-Aminoacyl-tRNA Complex
od: José Manuel Mingot, et al.
Izdano: (2013-11-01)

eEF1A Mediates the Nuclear Export of SNAG-Containing Proteins via the Exportin5-Aminoacyl-tRNA Complex
od: José Manuel Mingot, et al.
Izdano: (2014-08-01)

Needle-free vaccination: formulation and dermal delivery of diphtheria toxin CRM197 mutant
od: Weissmueller, NT
Izdano: (2013)

The number of PON1 mutant alleles, but not PON1 phenotype, is associated with Gensini score of coronary damage
od: Ilea Irina, et al.
Izdano: (2013-12-01)

CRM unplugged: releasing CRM's strategic value /
od: 416883 Bligh, Philip, et al.
Izdano: (2004)

Simultaneous induction of mutant alleles of two allergenic genes in soybean by using site-directed mutagenesis
od: Shota Sugano, et al.
Izdano: (2020-11-01)