X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate.

X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate.

Studies on the catalytic mechanism and inhibition of serine proteases are widely used as paradigms for teaching enzyme catalysis. Ground-breaking work on the structures of chymotrypsin and subtilisin led to the idea of a conserved catalytic triad formed by the active site Ser, His and Asp residues....

书目详细资料
Main Authors:	Wilmouth, R, Edman, K, Neutze, R, Wright, P, Clifton, I, Schneider, T, Schofield, C, Hajdu, J
格式:	Journal article
语言:	English
出版:	2001

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