Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I.

Transcription termination by RNA polymerase I in Saccharomyces cerevisiae is mediated by a 'torpedo' mechanism: co-transcriptional RNA cleavage by Rnt1 at the ribosomal DNA 3'-region generates a 5'-end that is recognized by the 5'-3' exonuclease Rat1; this degrades the...

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Bibliographic Details
Main Authors: Braglia, P, Heindl, K, Schleiffer, A, Martinez, J, Proudfoot, N
Format: Journal article
Language:English
Published: 2010