Complement inhibitor of C5 activation from the soft tick Ornithodoros moubata.

Blood-feeding ticks must control C activation or be damaged by the host inflammatory response. We report the characterization and expression of a novel, relatively small, broad-acting C inhibitory protein (termed OmCI) from the soft tick Ornithodoros moubata. The native 17-kDa nonglycosylated protei...

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Detalles Bibliográficos
Main Authors: Nunn, M, Sharma, A, Paesen, G, Adamson, S, Lissina, O, Willis, A, Nuttall, P
Formato: Journal article
Idioma:English
Publicado: 2005