Seasonal Childhood Anaemia in West Africa Is Associated with the Haptoglobin 2-2 Genotype

BACKGROUND: Anaemia is a major cause of morbidity and mortality for children in Africa. The plasma protein haptoglobin (Hp) binds avidly to free haemoglobin released following malaria-induced haemolysis. Haptoglobin polymorphisms result in proteins with altered haemoglobin-binding capacity and diffe...

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Bibliographic Details
Main Authors: Atkinson, S, Rockett, K, Sirugo, G, Bejon, P, Fulford, A, O Connell M, A, Bailey, R, Kwiatkowski, D, Prentice, A
Format: Journal article
Language:English
Published: Public Library of Science 2006