Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface

Lipopolysaccharide (LPS) O-antigen (O-Ag) is known to limit antibody binding to surface antigens, although the relationship between antibody, O-Ag and other outer-membrane antigens is poorly understood. Here we report, immunization with the trimeric porin OmpD from Salmonella Typhimurium (STmOmpD) p...

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Bibliographic Details
Main Authors: Domínguez-Medina, CC, Pérez-Toledo, M, Schager, AE, Marshall, JL, Cook, CN, Bobat, S, Hwang, H, Chun, BJ, Logan, E, Bryant, JA, Channell, WM, Morris, FC, Jossi, SE, Alshayea, A, Rossiter, AE, Barrow, PA, Horsnell, WG, MacLennan, CA, Henderson, IR, Lakey, JH, Gumbart, JC, López-Macías, C, Bavro, VN, Cunningham, AF
Format: Journal article
Language:English
Published: Springer Nature 2020