The ATP-sensitivity of K+ channels in rat pancreatic B-cells is modulated by ADP.

ATP-sensitive K+ channels in inside-out membrane patches from dispersed rat pancreatic B-cells were studied using patch-clamp methods. The dose-response curve for ATP-induced channel inhibition was shifted to higher concentrations in the presence of ADP (2 mM). In glucose-free solution, the total in...

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Bibliographic Details
Main Authors: Kakei, M, Kelly, R, Ashcroft, S, Ashcroft, F
Format: Journal article
Language:English
Published: 1986