Biocatalytic reductive amination as a route to isotopically labelled amino acids suitable for analysis of large proteins by NMR

<p>We demonstrate an atom-efficient and easy to use H<small><sub>2</sub></small>-driven biocatalytic platform for the enantioselective incorporation of&nbsp;<small><sup>2</sup></small>H-atoms into amino acids. By combining the biocatalytic de...

Full description

Bibliographic Details
Main Authors: Rowbotham, JS, Nicholson, JH, Ramirez, MA, Urata, K, Todd, PMT, Karunanithy, G, Lauterbach, L, Reeve, HA, Baldwin, AJ, Vincent, KA
Format: Journal article
Language:English
Published: Royal Society of Chemistry 2023