Formation of the venous pole of the heart from an Nkx2-5-negative precursor population requires Tbx18.

The venous pole of the mammalian heart is a structurally and electrically complex region, yet the lineage and molecular mechanisms underlying its formation have remained largely unexplored. In contrast to classical studies that attribute the origin of the myocardial sinus horns to the embryonic veno...

Full description

Bibliographic Details
Main Authors: Christoffels, V, Mommersteeg, M, Trowe, M, Prall, O, de Gier-de Vries, C, Soufan, A, Bussen, M, Schuster-Gossler, K, Harvey, R, Moorman, A, Kispert, A
Format: Journal article
Language:English
Published: 2006