A novel desmocollin-2 mutation reveals insights into the molecular link between desmosomes and gap junctions.

BACKGROUND: Cellular adhesion mediated by cardiac desmosomes is a prerequisite for proper electric propagation mediated by gap junctions in the myocardium. However, the molecular principles underlying this interdependence are not fully understood. OBJECTIVE: The purpose of this study was to determin...

Full description

Bibliographic Details
Main Authors: Gehmlich, K, Lambiase, P, Asimaki, A, Ciaccio, E, Ehler, E, Syrris, P, Saffitz, J, McKenna, W
Format: Journal article
Language:English
Published: 2011