Inhibitory killer cell immunoglobulin-like receptors strengthen CD8+ T cell–mediated control of HIV-1, HCV, and HTLV-1

Killer cell immunoglobulin-like receptors (KIRs) are expressed predominantly on natural killer cells, where they play a key role in the regulation of innate immune responses. Recent studies show that inhibitory KIRs can also affect adaptive T cell–mediated immunity. In mice and in human T cells in v...

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Bibliographic Details
Main Authors: Boelen, L, Debebe, B, Silveira, M, Frater, A, al., E
Format: Journal article
Published: American Association for the Advancement of Science 2018