Fission yeast Pds5 is required for accurate chromosome segregation and for survival after DNA damage or metaphase arrest.
Sister chromatid cohesion, which is established during the S phase of the eukaryotic cell cycle and persists until the onset of anaphase, is essential for the maintenance of genomic integrity. Cohesion requires the multi-protein complex cohesin, as well as a number of accessory proteins including Pd...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
2002
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