Searching for the ideal triazole: investigating the 1,5-triazole as a charge neutral DNA backbone mimic

A novel triazole linkage that mimics the phosphodiester backbone in DNA was designed, synthesised and evaluated. Unlike previous work which utilised copper to form a 1,4 triazole linkage in the DNA backbone, a ruthenium catalyst was used to yield a 1,5 triazole. The artificial linkage was incorporat...

詳細記述

書誌詳細
主要な著者: Baker, YR, Traoré, D, Wanat, P, Tyburn, A, El-Sagheer, AH, Brown, T
フォーマット: Journal article
言語:English
出版事項: Elsevier 2019