Searching for the ideal triazole: investigating the 1,5-triazole as a charge neutral DNA backbone mimic
A novel triazole linkage that mimics the phosphodiester backbone in DNA was designed, synthesised and evaluated. Unlike previous work which utilised copper to form a 1,4 triazole linkage in the DNA backbone, a ruthenium catalyst was used to yield a 1,5 triazole. The artificial linkage was incorporat...
主要な著者: | , , , , , |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
Elsevier
2019
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