Genome-wide genetic association of complex traits in heterogeneous stock mice.

Difficulties in fine-mapping quantitative trait loci (QTLs) are a major impediment to progress in the molecular dissection of complex traits in mice. Here we show that genome-wide high-resolution mapping of multiple phenotypes can be achieved using a stock of genetically heterogeneous mice. We devel...

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Bibliographic Details
Main Authors: Valdar, W, Solberg, L, Gauguier, D, Burnett, S, Klenerman, P, Cookson, W, Taylor, MS, Rawlins, J, Mott, R, Flint, J
Format: Journal article
Language:English
Published: 2006