Immunization against GAD induces antibody binding to GAD-independent antigens and brainstem GABAergic neuronal loss

Stiff person syndrome (SPS) is a highly-disabling neurological disorder of the CNS characterized by progressive muscular rigidity and spasms. In approximately 60–80% of patients there are autoantibodies to glutamic acid decarboxylase (GAD), the enzyme that synthesizes gamma-amino butyric acid (GABA)...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Chang, T, Alexopoulos, H, Pettingill, P, McMenamin, M, Deacon, R, Erdelyi, F, Szabó, G, Buckley, C, Vincent, A
स्वरूप: Journal article
भाषा:English
प्रकाशित: Public Library of Science 2013